SDI Antibody Production and Services


Strategic Diagnostics Announces Success in Demonstrating Utility of its Proprietary Genomic Antibodies™ Reagents on Clinical Samples in Cooperation with the Human Protein Atlas

NEWARK, Del., April 30, 2007 - Strategic Diagnostics Inc. (Nasdaq: SDIX) today announced the successful use of a number of its antibody reagents on clinical samples in studies being conducted by the Swedish Human Protein Atlas (HPA) program of the Human Proteome Resource (HPR) Center located in Stockholm, Sweden. The reagents, produced using SDI's proprietary Genomic Antibody Technology™, specifically target a selection of cancer associated proteins. The antibodies were studied in the HPA's tissue-profiling program and generated high resolution immunohistochemistry images across a wide spectrum of normal and cancerous tissues. Analyses of immunohistochemistry images are standard tests performed by pathology laboratories to diagnose disease. For each antibody, 576 spots of human tissue from 360 different individuals were treated and stained.

Images created in the analysis clearly demonstrated the ability of antibodies generated by SDI's high throughput Genomic Antibody Technology™ to differentially stain cancer-associated proteins in patient tissue samples. The antibodies are created by using a proprietary system that produces recombinant protein inside the host animal, thereby activating an immune response to the encoded protein. This allows the production of antibodies generated against the protein's native structure, rather than traditional methods that produce antibodies to synthesized surrogates. Among the advantages of the Genomic Antibody Technology™ is its ability to enable the development of reagents against traditionally difficult cellular targets, such as highly conserved and transmembrane proteins. The system is highly scaleable, allowing the generation of custom libraries consisting of hundreds of antibodies for use in the drug discovery, diagnostic, and research markets. SDI is currently developing a significant number of these innovative reagents to be offered via a web-based catalog.

Matthew H. Knight, the Company's President and Chief Executive Officer, commented, "The demonstrated advantages of our Genomic Antibody Technology™ continue to produce real-world data to differentiate our antibody reagents from antibody reagents generated by traditional means. The HPA data is more evidence that our antibodies can perform under rigorous study conditions." Strategic Diagnostics offers custom service access to its Genomic Antibody Technology™ for polyclonal and monoclonal products.



About Strategic Diagnostics Inc.
Strategic Diagnostics Inc. is a leading provider of antibody technology to the Life Science market place. Additionally the company provides biotechnology-based detection solutions for a broad range of food, water, agricultural, and environmental applications. By applying its core competencies of antibody and assay development, the Company produces unique, sophisticated reagents, reagent systems, antibody design services and bio-detection solutions to customer needs. Customers benefit from the enablement of their research into critical health care challenges of disease understanding, therapeutic development and diagnostic discovery. Industrial customers benefit with quantifiable "return on investment" by reducing time, labor, and/or material costs. All this is accomplished while increasing accuracy, reliability and actionability of essential test results. The Company is focused on sustaining this competitive advantage by leveraging its expertise in antibody design, immunology, proteomics, bio-luminescence and other bio-reactive technologies to continue its successful customer-focused research and development efforts. Recent innovations in high throughput production of antibodies from genetic antigens will complement the Company's established leadership in commercial and custom antibody production for the Research, Human/Animal Diagnostics, and Pharmaceutical industries, and position the Company for broader participation in proteomics research and discovery.



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