Antibody Fragmentation
Purified monoclonal antibodies can be fragmented to Fab or F(ab')2 fragments when assay background is high or when the binding of the full-size antibody is hindered by its size. Antibody fragments may more easily leave blood vessels and penetrate tissues. The Fab fragment is monovalent (contains a single binding site) while the F(ab')2 fragment is divalent. Let us determine the appropriate fragmentation conditions for your antibody.
Fragmentation Pricing
Mass of Starting Whole Antibody
<20 mgs
21-50 mgs
51-100 mgs
>100 mgs
F(ab')2 fragments
$665
$800
$960
$9.50/mg
F(ab) fragments
$665
$800
$960
$9.50/mg
Our Genomic Antibody Technology™ process can produce difficult antibodies faster and at lower cost.
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